|
KMID : 1144120170070020081
|
|
Biomedical Engineering Letters
2017 Volume.7 No. 2 p.81 ~ p.89
|
|
|
Limitations and artifacts in shear-wave elastography of the liver
|
|
Bruce Matthew
Kolokythas Orpheus
Ferraioli Giovanna
Filice Carlo
O’Donnell Matthew
|
|
|
Abstract
|
|
|
|
Recent studies have shown that real-time, two-dimensional shear-wave elastography (2D-SWE) can monitor liver fibrosis by measuring tissue elasticity (i.e., elastic modulus). Two clinical studies of 2D-SWE in the liver have shown that there are several practical issues that can compromise quantitation of liver tissue elasticity. Both general ultrasound (US) limitations and limitations in the 2D-SWE method itself resulted in significant variability in estimated liver elasticity. The most common US limitations were: poor acoustic window, limited penetration, and rib/lung shadows. The most common 2D-SWE limitations were: reverberations under the liver capsule, respiratory/cardiac motion, and vessel pulsation/loss of SWE signal. Based on these studies, scan protocols have been optimized to minimize the influence of these limitations on liver elasticity quantification. These refined protocols should move non-invasive SWE closer to becoming the preferred tool to diagnose and manage many chronic diseases of the liver.
|
|
|
KEYWORD
|
|
|
Fibrosis, Shear-wave elasticity imaging, Acoustic radiation force, Shear modulus, Shear-wave speed, Liver stiffness
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|